Poster – Metabolism and Tumour Biology
(DNA sequences obtained after PCR analysis of DNA extracted from patient’s glioma biopsy)
How will you analyse and display this data?
How can you tell if there is a difference between the different samples? (Statistical analysis)
What does this tell you about the activity of the enzyme?
Write a figure legend and descrbe and interpret the results.
Figure 3: Anti-IDH1 immunohistochemistry
(The micrograph)
What does this show?
How will you analyse and display this data?
How can you tell if there is a difference between the different samples
What does this tell you?
This will be graphical representation of the data in figure 4: The levels of 2-HG. Give the figure a title and a legend. What do they mean?
How is it related to the patient
Why is there experimental data on 2-HG
How will you analyse and display this data?
How can you tell if there is a difference between the different samples
What does this tell you?
What is HIF1a activity
Why are we measuring HIF1a activity and conducting this experiment
Figure 6: Expression levels of cyclin D1, vascular endothelial growth factor (VEGF) and platelet-derived growth factor A (PDGFA) in IDH1-mutated tumor lysates obtained from glioma patient and normal brain
(Western blot)
What does this show?
How is this related to the patient and the other data
What does this mean for the patient?
What is the likely prognosis and treatments possible for the patient?
