Are all relevant papers identified in the review?
How is the quality of the papers assessed?
How are the results summarized?
Does the review address a clearly focused research question?
What are the inclusion and exclusion criteria for studies?
Are the interventions similar between studies?
Is it reasonable to combine the studies?
What measures of occurrences or exposure are reported in each study?
Are the magnitude and precision of the effects reported?
Are participants in the review studies similar to your patients?
Are all important outcomes considered?
Would you consider a change in practice based on the results?
