Category: Biology

Rate the company according to the 5 star rating system used in the Fortune 500 list, stating how many stars would you rate the mission statement. Explain your rationale?

Mission Statements

Prior to completing this assignment, review Chapter 2, section 2.1 in your Constellation textbook and read the article Answer 4 Questions to Get a Great Mission Statement (Hull, 2013), being sure to review this Fortune 500 Mission Statements Now, turning to the company you selected, research and find the company’s mission statement. Then,

State how the mission statement provides guidance for the company’s organizational activities.

Evaluate the company’s mission statement per each of the four questions posed in the Hull article as well as your assigned readings for the week.

Rate the company according to the 5 star rating system used in the Fortune 500 list, stating how many stars would you rate the mission statement. Explain your rationale.

Rewrite the mission statement so that it better addresses the four questions and forms a complete mission statement.

Discuss the safety profile, mechanism of action (pharmacology) of each drug and the side effects of therapy and improved options that may be avail be in the future. Most effective treatements in all indications currently etc.

Pharmacology

Discussion section of the report using the introduction and results and methods section for guidance focus on the adverse events profiles of each drug mentioned and finish off with what drugs are currently in the pipeline and how they would change the face of arthritis therapy. Use the “Discussion instructions” for more guidance on style of writing etc.

The introduction and methods and results are the these sections of this report with the main aim of comparing Rheumatoid arthritis therapies.

The main aim of the research will be to investigate which options are considered better for individuals who are currently suffering from RA. This will focus on both types of therapeutic options for rheumatoid arthritis, monoclonal antibody, and small molecule therapy.

Discuss the safety profile, mechanism of action (pharmacology) of each drug and the side effects of therapy and improved options that may be avail be in the future. Most effective treatements in all indications currently etc.

Critically analyse and synthesise scientific information in the subject area of biotechnology and articulate and present this effectively, through written, oral and digital formats, to a diverse and global audience.

Journal club presentation – MicroRNA-19a contributes to the epigenetic regulation of tissue factor in diabetes By Marco Witkowski, Termeh Tabaraie, […], and Ursula Rauch

1. Demonstrate an understanding of a number of aspects of biotechnology and apply knowledge to problem based scenarios.

2. Critically analyse and synthesise scientific information in the subject area of biotechnology and articulate and present this effectively, through written, oral and digital formats, to a diverse and global audience.

You will be randomly allocated a scientific paper, via Aula. You will prepare and deliver a minimum 20 minute (plus 5 minute questions) presentation on this Biotechnology-related journal article, to be presented as an individual.

You should attempt to explain the paper, including techniques used, to the audience, and be ready to answer detailed questions on the content of the paper.

You are required to submit an electronic copy of your presentation, at least 24 hours before the oral presentation takes place, through the TurnItInUK link on the 7024BMS Moodle web-page (under the assessment tab).

You will also be required to give your oral presentation in person, and to answer questions on it.

Explain the background briefly, and then to focus on the specific research question addressed by the paper, and particularly on the techniques used and the details of the data generated, followed by a discussion of the significance and implications of the findings.

The times, rooms and dates for the presentations will be communicated via Aula.

Convert your final submission to a PDF format as these suffer less from formatting changes.
remember that submission can take time to complete, and therefore ensure you do this early.

The TurnitinUK system will record the date and time of your submission and cannot be over-written.

Ensure that the presentation you give in person is identical to the one that you submit through TurnItInUK.

Describe the generic and employability skills developed through this work.

Research Proposal

Project Details
provide an outline of the project and relevance of the proposed work to the subject domain postgraduate programme.refer to guidelines for further details. (Maximum 500 words)

Programme of Work
Provide a detailed description of the proposed work programme. refer to guidelines for further details. (Maximum 500 words)

Employability
Describe the generic and employability skills developed through this work. (Maximum 100 words)

A Note on Funding, Ethics and Safety: Although not a required part of this assessment, when formulating your Proposal you should consider whether your research will require any particularly expensive materials (e.g. ELISA kits, antibodies, chemicals).

You should also consider whether there are any ethical implications to your research, and if so make sure you understand the procedures required to obtain approval. (Ethical approval is always required for research involving human subjects and/or human tissue).

The potential use of any hazardous procedures or materials should be taken into account and justified, and suitable control measures identified before your research takes place.

 

Discuss these with each other or your supervisor-Analyse your plasmid DNA using agarose gel electrophoresis,

Genetics

BI2S109 Human Molecular Genetics

From gene to protein: overexpressing insulin and green fluorescent protein

Objectives
In these practicals you will learn how to:

• Set up a PCR and amplify a human gene,

• Set up a restriction digest,

• Ligate an insert into a plasmid vector and to transform bacteria,

• Use antibiotics to screen for transformants,

• Regulate the expression of the INS or GFP gene using arabinose,

• Calculate transformation efficiency,

• Isolate a plasmid,

• Analyse your plasmid DNA using agarose gel electrophoresis,

Overview
Prac 1
• Set up and perform PCR

• Digest plasmid with NheI to open plasmid between Ara promoter and GFP

• Check digest on gel
Prac 2
• Cut PCR fragment with NheI

• Ligate PCR product in plasmid

• Transform E. coli with plasmid on Ara/Amp plates

• Select glowing/non-glowing colonies (not actually happening in the prac)
Prac 3 (3hrs)
• Plasmid DNA extraction

• Restriction digest of plasmid

• Check digest on agarose gel

• Pick colony and plate bacterial cells on plates with and without arabinose

Will be completed for you and results made available to you on Blackboard:

• Check GFP production by glow

• Check GFP or Insulin protein production by protein SDS PAGE gel electrophoresis

• Transfer proteins to Western blot membrane

• Western blot detection

You need to record all the work in your lab book which you can use to write the lab report.

The questions in this manual are there to help to understand the practical.

Discuss these with each other or your supervisor.

Introduction
In this lab you will perform

Provide an example of an invasive species found in the biome/ecosystem. What are some of the negative impacts this invasive species has on the ecosystem? What is being done to mitigate impacts?

Biomes and ecosystems

Pick a biome and ecosystem and create a 500-700 word essay addressing the following:

Provide one example of a keystone species found in the biome/ecosystem. Why is this keystone species important to the biome/ecosystem? What defines it as a keystone species?

Provide an example of an invasive species found in the biome/ecosystem. What are some of the negative impacts this invasive species has on the ecosystem? What is being done to mitigate impacts?

Provide one example of an endangered species found in the biome/ecosystem. Briefly discuss the causes of the decline in the species and what is being done to help.

include at least 3 academic sources and make sure all sources are cited in essay.

How does the asexual form of parasite A multiply? Draw and label a diagram to illustrate this.

parasitology

Parasitology Practical Questions (total marks 100) Using the information in the paragraph below you are expected to answer questions

relating to unknown parasite A. Parasite A is an intracellular organism but can also be found free in the blood and peritoneal exudate.

It can invade a wide array of cells but not red blood cells. Its definitive host is cat. Mammals and birds are intermediate hosts. Infection can remain in the body for life,commonly in an inactive form. In immunocompromised individuals, it can reactivate.

Question 1: What is the species name of parasite A? (5 marks)

Question 2: How is parasite A acquired by humans? (5 marks)

Questions 3: Draw and label a diagram to show the life cycle of parasite A in definitive and intermediate hosts (15 marks).

Question 4: Draw and label a diagram to show the rapidly growing form of parasite A. (5marks).

Question 5: How does the asexual form of parasite A multiply? Draw and label a diagram to illustrate this. (15 marks).

Question 6: Serologic analysis of a serum sample of a pregnant woman infected with parasite A can potentially generate one of the results summarised in each row as shown in

Table 1 below. For each row, comment on the clinical relevance of the positive or negative

IgG and IgM result, and add clinical recommendations (20 marks; 5 marks per row).

Table 1: IgM result IgG result Clinical relevance and recommendations

Negative Negative A (write your answer below)

Negative Positive B (write your answer below)

Positive or ambiguous Negative C (write your answer below)

Positive or ambiguous Positive D (write your answer below)

Question 7: Name two serological assays that can generate the results in the Table 1. (5
marks).

Question 8: Explain the principle behind one of the serological assays indicated in Question
7 above. (15 marks).

Question 9: Devise step by step instructions for the serological assay indicated in Question
8. (15 marks

Explain your reason for pursuing bachelors of science dental hygiene degree and state your long and short term career goals”

Short term and long term goals as a dental hygienist

The topic of the admission paper is “explain your reason for pursuing bachelors of science dental hygiene degree and state your long and short term career goals”

Mention how chose to pursue this degree because worked in an office setting and answering phone calls helping customers,was able to hear the instant relief in their voices but didn’t get to see the true results of their contentment after helping them.

Short term goals:
1. To learn more about oral care and preventative care and pass this information to others in my community, my family and friends.

2. To teach something new to students with the same passion, who will be working alongside me and to also learn something from them too.

3. Gain professional experience from this program

Long term goals:
1. To keep finding new ways to improve the quality of the dental care that am giving to my patients
2. Learning new procedures and equipment because the dental industry is ever-changing.
3. Continuing my education as a dental hygienist, learning about all the advancements in this industry.