Biology Archives - Page 9 of 18

Bahamians’ compliance with the Covid-19 vaccine mandate:Discuss?

Assessing RTS, S/AS01 (Mosquirix) Vaccine’s Efficacy for Children Against Malaria in Africa:Discuss?

How and/or why HMM could be useful in Biotechnology?Discuss pros and cons of PSI-BLAST in compared to the regular protein BLAST (blastp)?

Bioinformatic Homework

How and/or why HMM could be useful in Biotechnology?

In your opinion, what are the pluses and minuses for Delta-BLAST compared to PSI-BLAST?

Discuss pros and cons of PSI-BLAST in compared to the regular protein BLAST (blastp)?

How would you assess homology in putative homologs found by PSI-BLAST.

What is the E value of the best matching proteasome? Based on the colors and the distribution, from which of the three domains of life are the majority of hits?

Bioinformatics

Run a Delta-BLAST with the silkworm insulin protein (P26726). Limit to human proteins in the RefSeq_Protein database.

How many total sequences?

How many human homologs appear to have the insulin domain (irrespective of the e-value threshold)?

Now edit search remove the human from the organism selection and change DELTA-BLAST threshold to 0.005. Keep everything else unchanged. How many records?

Write the name of the organism that has the best e-value?

Run a second iteration. What is the name of the newly added organism that has the best e-value? What is that e-value?

How many sequences? Write the name of the only organism that has an e-value of 1e-04.
Write the approximate number of new hits at each of the subsequent iterations.
Are there still sequences being added on the fifth iteration?
Are most of those descriptions “proteases?

Run hmmer with the proteasome from question 2. Search the RefSeq database.

What is the E value of the best matching proteasome?
Based on the colors and the distribution, from which of the three domains of life are the majority of hits?

The proteasome sequence is from a hyperthermophilic archaeon. Why do you suppose there may be a (relative) lack of total hits in archaea using HMMER?

How does the vaccine interact with the body to produce immunity?How are genes inserted into plant cells?

Hole in the ozone layer/Global Warming Research Paper

In your paper you should include a detailed description of your topic.

How are genes inserted into plant
cells?

How does the vaccine interact with the body to produce immunity?

How does gene therapy
work?

You should also include historic information. When was PCR invented?

What types of polio vaccines
were tried and failed before we succeeded?

What are the times, the dates, and the people involved? What was the world like before?

If your topic is relatively new, or something that is still being developed, you may want to include where
the future is heading.

Gene therapy isn’t commonly used now; why not? What needs to be perfected? How will that be done?

You should discuss the good and bad side of your topic (every topic has both!).

What benefits have we
gained from gene therapy?

What are the downfalls of the smallpox vaccine?

How can DNA profiling be
used in positive and negative ways?

Why did/are some people “all for” this topic?

Why are some
people dead set against it?

Make sure your closing paragraph wraps up all aspects of your paper nicely: what it is, how it affected the world, why it’s good and bad.

How Cas9 detects and cleaves DNA targets, and (eukaryotic) cellular responses to the resultant double strand DNA break:Discuss?

Is there good use of explanatory diagrams to further illustrate points being made and to summarise the information presented?

Galantamine

Has the work submitted adhered to the brief and covered all the aspects required?

Does the case study essay tell a logical story from start to finish?

Is the case study essay appropriately critical and does it discuss and show good understanding of the relevant issues. limitations and other concerns associated with the research and clinical trials undertaken?

Is there evidence of an appropriate level of further reading and correct, evidence-based argument within the case study?

Is there good use of explanatory diagrams to further illustrate points being made and to summarise the information presented?

Is the case study essay generally well written, concisely and in good scientific English without typos and grammatical errors?

Overall, does the case study engender interest from the reader and provide a conclusion that suggests further avenues for future research and development?

Efficacy Of The RTS,S/AS01 (Mosquirix™) Vaccine For Children Against Malaria In Africa:Discuss?

Include in your categorization whether or not this food is a “good” source of that macromolecule (i.e. does this include unsaturated vs. saturated fats? Is it a high source of protein? Overly processed?

What fuels you

Prompt
When considering the hierarchy of biological organization, macromolecules are the last abiotic (i.e. non-living) “step” before the smallest functional living units cells. If organisms were not able to obtain these macromolecules, either through synthesis or ingestion, life could not exist. For this discussion you will be building on the foundation of the previous Module by defining what macromolecules are and using your knowledge of their molecular structure to explore how they “fuel” us via the process of cellular respiration.
Include in your categorization whether or not this food is a “good” source of that macromolecule (i.e. does this include unsaturated vs. saturated fats? Is it a high source of protein? Overly processed?