Researchable Problem
PICOT Question
Question of Intervention
In ____________ (P), how does ___________ (I)
compared to _________ (C) affect ________ (O)
within __________ (T)?
Question of Intervention
In African-‐American female adolescents with
hepatitis B (P), how does acetaminophen (I)
compared to ibuprofen (C) affect liver function
(O)?
Question of Prognosis/Prediction
In ____________ (P), how does ___________ (I)
compared to _________ (C) influence/predict
________ (O) over __________ (T)?
PICOT Question
Question of Prognosis/Prediction
For patients 65 years and older (P), how does
the use of an influenza vaccine (I) compared to
not received the vaccine (C) influence the risk of
developing pneumonia (O) during flu season (T)?
PICOT Question
Question of Prognosis/Prediction
In patients who have experienced an acute
myocardial infarction (P), how does being a
smoker (I) compared to a non-‐smoker (C)
influence death and infarction rates (O) during
the first 5 years after the myocardial infarction
(T)?
Question of Diagnosis or Diagnostic Test
In ____________ (P), are/is___________ (I)
compared with _________ (C) more accurate in
diagnosing ________ (O)?
PICOT Question
Question of Diagnosis or Diagnostic Test
In middle-‐aged males with suspected myocardial
infarction (P), are serial 12-‐lead ECGs (I)
compared to one initial 12-‐lead ECG (C) more
accurate in diagnosing an acute myocardial
infarction (O)?
