1. Explain in your own words exactly how CRISPR works.
2. Do you agree or disagree that the controversy around CRISPR is similar to the controversy around cloning decades ago?
3. What is the Cas9 RNA base sequence that would attach the CRISPR complex to the following segment of DNA? (Hint: See Section 21.5 of eText)
Personal DNA Update. What’s new in Direct-to-Consumer Personal DNA testing? Do some research and share what you found out. Try to find some useful information that could help a person decide if Personal DNA testing is a good idea. A single source is fine; just sum it up briefly using your own personal style. To find a credible source, use ScienceDaily (Links to an external site.) or the Journalism sources (newspapers, magazines) shared in the Research-Based Writing Guide (https://goo.gl/VYyJas (Links to an external site.)). Quote properly or summarize and hyperlink to your source.
For the rest of the Post, research based information is not expected or required, you can respond using background gained from the videos and radio story coupled with your own personal concerns or experiences.
Personal DNA Benefits. In a paragraph, describe at least two important reasons why you personally WOULD or MIGHT want to have a personal DNA test done. Is there a family health issue you are concerned about? (Use best judgment in deciding how much to share). Is there another question such a test could help you answer for yourself or for your offspring?
Personal DNA Risks or Drawbacks. In a third paragraph, describe at least two important reasons that you personally WOULD NOT or MIGHT NOT want to have a personal DNA test done. What are some of your major concerns? Would you want to limit your information about specific issues?
In a final short paragraph, Answer the question: if you had to decide right now, would you have a free test and analysis of your SNPs? If you would accept a free test, what would you want to know based on the results? Explain your choice; what were the most important factors in your decision?
A DNA inspired cryptographic technique to secure data accessing for the cloud computing:Discuss?
Explain the relation between genomic DNA and RNA, describe what an intron is. What is the purpose of the experiment? Shortly summarise the outcome of the sequence analysis of rad21, do you think it has an intron? Explain the experimental design and how it should allow you to detect the absence or presence of the predicted intron.
What is the function of each of the main steps in the protocol? What is the expected result in case of the intron being present? What if the intron is absent? Methods (10 out of 100 Marks; Max 100 words)
Here you can refer to the protocol used in the practical. Describe any deviations (if any) from the protocol.
Results (25 out of 100 Marks; Max 500 words, excluding tables and figure legends) For each of the main steps, present any results you may have obtained. How much RNA did you purify?
How much genomic DNA? Present your calculations. Present the picture of the gel and label it properly: each lane should be labelled, mark the sizes of the DNA ladder. Provide a figure legend.
Determine the sizes of the bands that you can see and mention these in the text. Most importantly: describe and interpret your results in the main text, talk the reader through what you conclude from your data and why.
Discussion (25 out of 100 Marks; Max 500 Words)
How Cas9 detects and cleaves DNA targets, and (eukaryotic) cellular responses to the resultant double strand DNA break:Discuss?
WHAT IS THE PRIMARY DIFFERENCE BETWEEN FERMENTATION AND ANAEROBIC
RESPIRATION?
What is the relationship between a genome, a chromosome and genes?
Briefly describe the events that occur in each phase of interphase.
Describe the similarities and differences between the cytokinesis mechanisms found in animal cells versus those
in plant cells.
Outline the steps that lead to a cell becoming cancerous.
Compare and contrast the roles of the positive cell-cycle regulators negative regulators
Name the common components of eukaryotic cell division and binary fission.
Describe the process that results in the formation of a tetrad
In a comparison of the stages of meiosis to the stages of mitosis, which stages are unique to meiosis and which
stages have the same events in both meiosis and mitosis?
Animals and plants both have diploid and haploid cells. How does the animal life cycle differ from the alternation
of generations exhibited by plants?
Describe the structure of the eukaryotic DNA
Discuss the similarities and differences between eukaryotic and prokaryotic DNA
What advantages might there be to separate the processes? Whatadvantages might there be to have them occur together?
Explain DNA replication
Discuss the role of different enzymes and proteins in supporting DNA replication
Describe 3 different types of DNA mutations and 3 different types of DNA repair mechanisms
The Biology of the Cancer Cell Control Cycle
Determine the impact of organelle processes such as mitosis, cytokinesis, centrosome duplication, and DNA replication in cancer cells in the human body leading to cancer.
David Reimer.
Watch this video:
The transcript is here:
What is the difference between sex, gender and sexual orientation?
What is the power of DNA (genetics), and can our nurturing out-muscle it?
Based on this story, is gender the result of genetics or environment?
What do you make of the fact that “Brenda” was raised a girl and given female hormones (“she” was told they were vitamins), but grew up to marry a woman?
What does this suggest about the origins of sexual orientation?
Remember, we all will watch the video so I do not need a movie review.looking for students to think more deeply than a summary. What do you think about what happened and why? Integration of textbook and video material and critical thinking are key here.
Note: because this is an older video, you may encounter vocabulary that is not used today. If you wish, feel free to use/discuss more up to date terms/understanding of concepts.
Be sure to address all assignment prompts above. Content should be substantial.
Forensic Science
1. Explain the different categories of fibers. Provide a scenario where each of these types of fibers may be found at a crime scene and how they would be analyzed.
2. Describe in detail how and why NIBIN was developed as well has which government agency manages it. In what instances would it be used in a criminal investigation?
3. Discuss two forensic examinations (DNA analysis, ballistics, toxicology, or fingerprint analysis) used in the Michael Brown case. Be sure to address the forensic evidence that was examined and where it was located in the crime scene and what each examination revealed to investigators.
4. Explain how the use of DNA has advanced criminal justice investigations over the last few decades. Also discuss the limitations of DNA evidence.
