Is there enough evidence to state that many classifications of environmental chemicals can lead to decreased kidney function and does this influence drug metabolism?

Medical Toxicology

Is there enough evidence to state that many classifications of environmental chemicals can lead to decreased kidney function and does this influence drug metabolism?

Teratogens are not just chemicals, they also include any environmental factor that can produce a permanent abnormality in the structure or function in the embryo or fetus. Explain the consequences and mechanisms that make hyperthermia a teratogen.

Medical toxicology

Teratogens are not just chemicals, they also include any environmental factor that can produce a permanent abnormality in the structure or function in the embryo or fetus. Explain the consequences and mechanisms that make hyperthermia a teratogen.

Since genes from cancer cells are hypomethylated are we sure that the hypomethylation is the cause of the malignancy or a consequence of the cancer cells possessing altered metabolism?

Medical toxicology

Many cells exposed to chemicals experience hypomethylation and this enhances cell transformation. Since genes from cancer cells are hypomethylated are we sure that the hypomethylation is the cause of the malignancy or a consequence of the cancer cells possessing altered metabolism?