lab 1 organic chem 2
Calculation of Masses of Reactants. Where applicable, use the volume and the literature density of a liquid reactants to calculate the masses used – look up
the literature value for density, where needed. (2pts)
Calculation of Moles of Reactants and Product. Calculate moles for each reactant and the product. Molar masses can be calculated from the molecular formula and/or looked up. (3 pts)
Percent Yield Calculation. Based on moles of reactants and the stoichiometry of the reaction, determined the limiting reactant, and theoretical yield in moles. Then determine the percent yield for the reaction.
Discuss the regiochemical and stereochemical outcomes of the hydroboration/oxidation reaction. Include a complete curved arrow mechanism for both the hydroboration step and the oxidation step.What is the purpose of using a flame-dried apparatus and a drying tube during the
hydroboration reaction? What undesired reaction will occur if water is present?
Why is argon used to displace the air in the reaction apparatus for the hydroboration step? (2 pts)
Briefly describe how GC (gas chromatography) separates the compounds in the crude mixture. Based on this, why does 1-octanol have a higher retention time than 2- octanol? (3 pts)
Show the first step in the mechanism for hydroboration E-3-methylpent-2-ene, including the transition state. You don’t have to show the mechanism for the oxidation steps, but provide the alcohol (major product) produced after oxidation. (3 pts)
